Blood vessels in the adult retia

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Jan M. Provis, Trent Sandercoe, Anita E. To investigate the relationship between development of the perifoveal blood vessels and formation of the foveal depression.

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In the nerve fiber layer, round and ovoid cells extended processes parallel to ganglion cell axons. In the ganglion cell layer, ovoid and stellate cells exhibited anisotropic processes or a honeycomb network. The inner lamina of astrocytes developed ahead of the outer lamina, and both reached their final positions before birth.

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Please take this quick survey to tell us about what happens after you publish a paper. Journal of Neurocytology. Antibodies to glial fibrillary acidic protein GFAP have been used to study the shape and location of astrocytes in whole mount preparations of developing postnatal rabbit retina.

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Occlusion blockage of a retinal vein is a common cause of sudden painless reduction in vision in older people. The retina is the thin membrane that lines the inner surface of the back of your eye. Its function is similar to that of the film in a camera.

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The adult human fovea. A, Section through the adult fovea embedded in glycol methacrylate and stained with azure II and methylene blue. Retinal blood vessels are present on the upper foveal slope arrows but not on the lower slope or in the foveola.

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The vasculature of the central nervous system CNS is composed of vascular endothelial and mural cells which interact closely with glial cells and neurons. The development of the CNS vascularisation is a unique process which requires the contribution of specific regulators in addition to the classical angiogenic factors. The egfl7 gene is mainly detected in endothelial cells during physiological and pathological angiogenesis.

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Loss of Norrin signalling due to mutations in the Norrie disease pseudoglioma gene causes severe vascular defects in the retina, leading to visual impairment and ultimately blindness. While the emphasis of experimental work so far was on the developmental period, we focus here on disease mechanisms that induce progression into severe adult disease. The goal of this study was the comprehensive analysis of the long-term effects of the absence of Norrin on vascular homeostasis and retinal function. In a mouse model of Norrie disease retinal vascular morphology and integrity were studied by means of in vivo angiography; the vascular constituents were assessed in detailed histological analyses using quantitative retinal morphometry.

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Abnormal retinal vasculature and vitreous, in combination with aberrant vitreoretinal traction are factors in the development of late complications in adults with retinopathy of prematurity ROP. We wish to highlight this rare late complication of ROP, which was described in adults by Tasman 2 in and in neonates by Kingham 3 in A year-old woman attended eye casualty 6 months after uncomplicated cataract surgery with a 1-day history of floaters in her right eye, She was a high myope with a history of ROP twin birth, 10 weeks premature.

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Retinal haemorrhage is a disorder of the eye in which bleeding occurs in the retinathe light sensitive tissue, located on the back wall of the eye. A retinal hemorrhage can be caused by several medical conditions such as hypertensionretinal vein occlusion a blockage of a retinal veinanemialeukemia or diabetes. Retinal hemorrhages commonly occur in high altitude climbers, most likely due to the effects of systemic hypoxia on the eye.

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